Azithromycin (Zithromax)


  • Antibiotic


  • Macrolide


  • Mild to moderate infections

  • Upper Respiratory Tract Infections

  • Otitis media

  • Community-Acquired Pneumonia

  • Chlamydia

  • Pelvic Inflammatory Disease


  • None


  • Pregnancy category B

  • Counsel patient to finish all medication to prevent development of resistance

  • Do not use with aluminum or magnesium containing antacids

  • Do not use with astemizole or cisapride (ventricular arrythmias with macrolides)

Adverse Reactions (Side Effects):

  • Hypersensitivity

  • Gastrointestinal: nausea, vomiting, diarrhea

  • Vaginitis


  • Administered orally (tablets, powder for oral suspension) or IV

  • Adult:

    • 500mg on day 1 then 250mg qd days 2-5

  • Chlamydia: 1gm single dose

  • Gonnorrhea:  2gm single dose

  • CAP:  500mg IV qd x 2 days then 500mg po for up to 7-10 days total

  • PID:  500mg IV qd x 2 days then 250mg po for up to 7-10 days total

  • Child:

    • 10mg/kg/day 1 then 5mg/kg/day days 2-5 (usually 100-200mg day 1 then 50-100mg days 2-5)

    • For oral suspension:  empty stomach, refrigerate, shake well, good for 10 days only

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