Calcium chloride injection U.S.P.

Category:

  • Electrolyte and water

Description:

  • Electrolyte

Indications:

  • Treatment of hypocalcemia in conditions requiring a prompt increase in plasma calcium (10%)

  • Treatment of magnesium intoxication (10%)

  • Combat hyperkalemia as measured by electrocardiograph, pending correction of the increased potassium level in the extracellular fluid 91050

  • Cardiac resuscitation when weak or inadequate contractions return following defibrillation or when epinephrine injection has failed to strengthen myocardial contractions (10%)

Contraindications:

  • Cardiac resuscitation in presence of  ventricular fibrillation or in patients with existing digitalis toxicity

Precautions:

  • Pregnancy category C

  • Use with caution in digitalized patients

  • Inject slowly into large vein to help prevent irritation and cardiac syncope

Adverse Reactions (Side Effects):

  • With fast injection: tingling sensations, calcium taste, sense of oppression “heat wave”

  • Peripheral vasodilatation

Dosage:

Administered ONLY by SLOW intravenous injection (1 ml/min) and/or intraventricular injection.  It must not be injected into the myocardium.

  • Usual adult dose in hypocalcemic disorders 

    • 0.5-1g (5-10ml) at 1-3 day intervals, depending upon response.

  • Magnesium intoxication: 

    • 500mg (5ml) IV promptly; observe patient for signs of recovery before further doses given

  • Hyperkalemic ECG disturbances of cardiac function: 

    • Titrate according to ECG changes during administration

  • Cardiac resuscitation: 

    • IV 0.5-1g (5-10ml); or, inject 200-800mg (2-8ml) into the ventricular cavity

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