Fluconazole (Diflucan)

Category:

  • Antifungal

Description:

  • Antifungal

Indications:

  • Candidiasis therapy and prophylaxis

  • Crytococcal menigitis

  • Vaginal Candidiasis

Contraindications:

  • Known sensitivity to fluconazole 

Precautions:

  • Pregnancy category C

  • Culture specimens to determine causative organism, use emperically then continue or alter therapy as indicated.

Adverse Reactions (Side Effects):

  • Headache (13%)

  • Nausea (7%)

  • Abdominal pain (6%)

  • Diarrhea (3%)

Dosage:

Administered orally and as injectable

Adult

Vaginal Candidiasis: 

  • 150mg for one time dose

Oropharyngeal and Esophageal Candidiasis: 

  • 200mg on day 1, then followed by 100mg daily for 14 days

Other Candidiasis: 

  • Doses up to 400mg per day until cured

Crytpococcal Meningitis: 

  • 400mg on day 1, then followed by 200mg daily for ten to twelve weeks following culture-negative cerebral spinal fluid

Child:

  • 3 mg/kg for adult dose of 100mg

  • 6 mg/kg for adult dose of 200mg

  • 12 mg/kg for adult dose of 400mg

The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks

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