Iodoquinol (Yodoxin)

Category:

  • Miscellaneous

Description:

  • Amebicide

Indications:

  • Intestinal amebiasis

Contraindications:

  • Hypersensitivity to iodine, renal disease, hepatic disease

  • Severe thyroid disease, pre-existing optic neuropathy

Precautions:

  • Pregnancy category C; excretion into breast milk unknown

  • Thyroid disease

Adverse Reactions (Side Effects):

  • CNS: agitation, headache, malaise, peripheral neuropathy

  • EENT: blurred vision, optic atrophy, optic neuritis, retinal edema, sore throat

  • GI: abdominal cramps, anal itching, diarrhea, epigastric distress, gastritis, nausea, rectal irritation, vomiting

  • HEME: agranulocytosis (rare)

  • SKIN: alopecia, discolored skin, hair, nails; pruritis, rash

  • MISC: chills, fever, thyroid enlargement, vertigo

 

Dosage:

Administered orally: Poorly absorbed, excreted in feces

  • Adult:   PO 650mg 3 times daily after meals for 20 days, not to exceed 2g daily

  • Child:   PO 30-40 mg/kg/day in 3 divided doses for 20 days, not to exceed 1.95g in 24 hours for 20 days; do not repeat treatment before 2-3 weeks

    

 
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