Meperidine (Demerol)


  • Analgesic


  • Synthetic opiate agonist analgesic


  • Moderate to severe pain

  • Anesthesia adjunct for preoperative sedation


  • Patients with impaired respiratory function.


  • Pregnancy Category C

  • Use with caution in patients with atrial flutter and other superventricular tachycardias.

  • Patients will experience CNS effects of drowsiness and dizziness, therefore use caution with motor vehicle operation or other hazardous tasks.

  • Avoid prolonged, sustained usage to decrease addiction potential.

  • Use with caution with other CNS depressive medications.

Adverse Reactions (Side Effects):

  • Sedation

  • Dizziness

  • GI effects (nausea, vomiting, dry mouth)


Administered in smallest effective dose, as infrequently as possible and titrated to pain control

Administered orally, SQ, IM, slow IV, or slow IV infusion


  • Normal oral, SQ or IM: 50-150mg q3-4h as needed

  • Slow IV infusion 15-35mg per hour


  • 1.1-1.8 mg/kg q3-4h as needed

Preoperative, Anesthesia adjunct:

  • Adult: 50-100mg SQ or IM 30-90 minutes before anesthesia

  • Children: 1-2.2 mg/kg (up to adult dose) SQ or IM 30-90 minutes before anesthesia

Labor anesthesia:

  • 50-100mg SQ or IM when labor pain begins, repeat at 1-3 hour intervals if needed

The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks.

Back to Medical Corps Pharmacy Page