Methadone (Dolophine)


  • Analgesic


  • Synthetic opiate agonist analgesic


  • Severe pain

  • Heroin and Opiate detoxification


  • Patients with impaired respiratory function.


  • Pregnancy Category C

  • May induce pulmonary edema

  • Rapid administration may induce respiratory depression, therefore monitor patientís respiratory function.

  • Patients will experience CNS effects of drowsiness and dizziness, therefore use caution with motor vehicle operation or other hazardous tasks.

  • Use with caution with other CNS depressive medications.

  • Like any narcotic, may be addictive when used for prolonged periods of time (weeks to months).

Adverse Reactions (Side Effects):

  • Sedation

  • Dizziness

  • Constipation

  • Excessive sweating  


Administered orally, SQ, or IM

Pain relief:

  • Normal oral, SQ or IM: 2.5-10mg q3-4h as needed


  • Packaged as a dispersible tablet.

  • Diluted in oral liquid to decrease potential for IV abuse

The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks.

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