Thiabendazole (Mintezol)

Category:

  • Antihelmintic

  Indications:

  • Strongyloiiasis (threadworm)

  • Cutaneous larva migran (creeping eruption)

  • Visceral larva migrans

Precautions:

  • Pregnancy category C

  • Monitor patients with hepatic or renal dysfunction.

  • Helminthic infections are very communicable.  Treat the entire family/household.

  • Adhere to strict hygiene to prevent re-infection.

  • Not necessary to use a post-therapy laxative to assist in purging of worms.

Adverse Reactions (Side Effects):

  • Headache, dizziness, drowsiness, psychic disturbances

  • Rash, pruritis

  • GI upset (anorexia, nausea, vomiting, diarrhea, cramping/pain)

  • Hematuria, enuresis, malodorous urine (asparagus-like smell)

  • Tinnitis, fever, visual changes

Dosage:

Administered orally

Adult:

  • <68 kg: 22mg/kg per dose for 2 doses a day for 2 consecutive days

  • >68kg: 1.5 grams per dose for 2 doses a day for 2 consecutive days

Visceral:

  • Administer same dosing guidelines, except continue therapy for 7 days

 
Back to Medical Corps Pharmacy Page