Sertraline Hydrochloride (Zoloft)

Category:

  • Antidepressant

Description:

  • SSRI (Selective serotonin uptake inhibitor)

Indications:

  • Depression

  • Obsessive-compulsive disorder

  • Panic disorder

Contraindications:

  • Concurrent use of MAO inhibitors

Precautions:

Adverse Reactions (Side Effects):

  • Insomnia

  • Decreased libido

  • Ejaculatory failure

  • Nausea

  • Fatigue

  • Dry mouth

  • Dizziness

  • Nausea

Dosage:

Administered orally (tablets)

Adult:

  • Depression: 50 mg PO QD

  • Obsessive-compulsive disorder: 50 mg PO QD

  • Panic disorder: 25 mg PO QD x 1 week, then 50 mg PO QD

Patients not responding after one week of therapy may benefit from increased daily dosage, not to exceed 200 mg/day. 

Therapeutic effects may not appear for a week or longer after initiating therapy. Changes in dosage should not be made more often than weekly.

 
Back to Medical Corps Pharmacy Page