Calcium Carbonate (Os-Cal, various)

Category:

Miscellaneous

Description:

Nutritional supplement

Indications:

Chronic hypocalcemia

Nutritional supplement

Hyperphosphatemia

Osteoporosis prophylaxis

Contraindications:

Hypercalcemia, hypercalciuria, hyperparathyroidism, bone tumors

Ventricular fibrillation, renal calculi

Precautions:

Pregnancy category C

GI obstruction, decreased GI motility

Fluid restriction

Adverse Reactions (Side Effects):

CV: bradycardia, cardiac arrest, dysrhythymias, shortened Q-T

GI: anorexia, constipation, diarrhea, eructation, flatulence, vomiting

GU: renal stones, renal failure, renal dysfunction

METAB: hypercalcemia, muscle weakness, headache, coma

Dosage:

Administered orally

  • Chronic hypocalcemia: Dosage is based on the clinical condition of the patient and the serum calcium concentration.  Serum concentrations of ionized calcium may be necessary to guide dosage adjustments in some patients, especially those with hypoalbuminemia.

    • Adult: Usual initial doses are 2-4 g PO of elemental calcium daily (5-10g carcium carbonate) administered in 3-4 divided doses

    • Child: 45-60 mg/kg PO of elemental calcium (112.5-162.5 mg/kg calcium carbonate daily, administered in 4 divided doses

    • Neonate: 50-150 mg/kg PO of elemental calcium (125-375 mg/kg calcium carbonate) daily, administered in 4-6 divided doses

  • Nutritional Supplementation (recommended daily allowance):

    • Adult >25 years: 1000-1500mg PO elemental calcium (2500-3750mg calcium carbonate) daily

    • Child > = 11 years and adults < = 24 years: 1200-1500mg elemental calcium (3000-3750mg calcium carbonate) daily

    • Child 6-10 years: PO 800-1200mg elemental calcium (2000-3000mg calcium carbonate) daily

    • Child 1-5 years: PO 800mg elemental calcium (2000mg calcium carbonate) daily

    • Infant 6-12 months: PO 600mg elemental calcium (1500mg calcium carbonate) daily

    • Infant <6 months: PO 400mg elemental calcium (1000mg calcium carbonate) daily

  • Osteoporosis prophylaxis: (in postmenopausal women)

    • Adult:  PO 1-1.5g elemental calcium daily

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