Levonorgestrel and Ethinyl Estradiol (Nordette)

Category:

  • Hormonal

Description:

  • Monophasic oral contraceptive

  • Nordette: levonorgestrel 0.15mg, ethinyl estradiol 30mcg

Indications:

  • Contraceptive

Contraindications:

  • Pregnancy and lactation

  • Undiagnosed abnormal vaginal bleeding

  • Known or suspected benign or malignant liver tumors while on oral contraceptive use

  • Breast carcinoma or estrogen-dependent neoplasia
  • Current or history of thromboembolic disorders, cerebral vascular or cardiovascular disease.

Precautions:

  • Pregnancy category X

  • Take as directed at intervals not exceeding 24 hours.  Efficiency is dependent upon strict compliance.

  • Breakthrough bleeding (“spotting”) may occur during initiation of therapy.

  • Instructions for missed doses:

    • One missed dose: Take as soon as possible or two tablets the next day and continue

    • Two missed doses: Take two tablets daily for two days, then continue normal schedule

    • Three missed doses: Discontinue therapy and begin new packet 7 days following last dose

  • May cause mental depression, fluid retention and depressed folate levels

  • Twenty-eight day packs contain seven days of inert ingredients to maintain regimen

  • Begin therapy on the fifth day of the cycle.  Day one of cycle is the first day of menstrual bleeding.

Adverse Reactions (Side Effects):

  • Abdominal cramping, anorexia, nausea, vomiting

  • Acne

  • Edema, weight gain

  • Unusual tiredness or weakness

  • Cardiovascular disorders (hypertension)

  • Thromboembolic disorders

Dosage:

Administered orally

  • One tablet daily for 21 or 28 days beginning on the fifth day of the cycle

Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C.
20372-5300

Operational Medicine 2001
 Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
 May 1, 2001

United States Special Operations Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323

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